Prevention of tumor growth and dissemination by in situ vaccination with mitochondria-targeted atovaquone

Atovaquone, an FDA-approved drug for malaria, is known to inhibit mitochondrial electron transport. In this study, the synthesized mitochondria-targeted atovaquone (Mito-ATO) increased mitochondrial uptake in both cancer cells and immunosuppressive…

Continue ReadingPrevention of tumor growth and dissemination by in situ vaccination with mitochondria-targeted atovaquone

Monitoring Crystallization Processes in Confined Porous Materials by Dynamic Nuclear Polarization Solid-State Nuclear Magnetic Resonance

Researchers from the SACS and CMO teams showed that solid-state NMR, combined with the sensitivity enhancement of dynamic nuclear polarization (DNP), enables efficient detection of metastable, transient species formed at…

Continue ReadingMonitoring Crystallization Processes in Confined Porous Materials by Dynamic Nuclear Polarization Solid-State Nuclear Magnetic Resonance