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L’équipe PCR recherche des candidats pour un poste de titulaire (chaire de professeur junior) manifestant un intérêt marqué pour les projets de chimie médicinale anti-infectieuse ou anticancéreuse impliquant, entre autres, les radicaux liés à la synthèse ou au mécanisme d’action de molécules bioactives. Ces projets de chimie médicinale pourront tirer parti d’approches innovantes telles que le ciblage de l’ARN, la dégradation ciblée des protéines (PROTAC) ou la régulation épigénétique…
New approaches in chemistry biology for the design of therapeutic molecules and their vectorization.
The Institute of Radical Chemistry , ICR (UMR7273), is a Joint Research Unit between the University of Aix Marse ille (AMU) and the National Center for Scientific Research (CNRS). From a scientific point of view, ICR bring s together the complementary skills of research teams specialized in radical chemistry , including synthesis of new molecules and materials, charact erization with state of the art spectroscopic and computational methods and applications in challenging areas (sustainable polymers, long lived radicals as drugs, photocatalysis .
Among the 8 ICR research teams, the Radical Pharmaco Chemistry team of ICR, localized on the Health campus Timone in Marseilles (Faculty of Pharmacy), mainly focuses on medicinal chemistry research devoted to get ting new anti infective or anticancer molecules. The research performed by the PCR team is structured along two main axes: the development of new synthetic methods mirroring the design of new organic electron donors and the preparation of new molecules with potential anti infective or anti cancer activity .
The PCR team is looking for candidates to a Tenure Track p osition Chaire Professeur Junior showing a keen interest for anti infective or anti cancer medicinal chemistry projects involving , but not limited to, radicals concerning the synthesis or the mechanism of action of bioactive molecules These medicinal c hemistry projects will be able to take advantage of innovative approaches such as RNA targeting, targeted protein degradation PROTAC or epigenetic regulation …
Candidates are invited to submit a competitive and innovative research proposal ideally integrating with the PCR team and the broader ICR and Health campus Timone ecosystem. Applicants must hold a PhD, substantial postdoctoral experience, a strong publication record, and the potential to secure external funding.
The Junior Professor Contract position offers attractive start up support and a dynamic, collaborative research environment. In accordance with the requirements of the call , candidate s must submit their application to AMU independently of any research unit but must specify and motivate in the proposal their intention to join a particular laboratory and team.
Expressions of interest are welcome from candidates wishing to join the Radical Pharmaco Chemistry (PCR) team: please do not hesitate to contact Prof. Thierry Terme (PCR) thierry.terme@univ amu.fr and/or Prof. Nicolas Ferré (Director of the ICR) nicolas.ferre@univ amu.fr to discuss the project you would like to develop and to gain effective support to your application.
Candidates must also formally apply via the ODYSSEE website.
Application Deadline: September 1 st 2025