Institute of Radical Chemistry

Research at the Institute of Radical Chemistry focuses on compounds carrying unpaired electrons. We master their structure through synthesis, characterization and simulations to access a broad range of applications, from advanced materials to therapeutic uses.

ICR Numbers

8 research teams working at the interfaces of radical chemistry, organic synthesis, simulations, materials or even biology.
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A la Une

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ICR thanks the Roger PELLENC Foundation for supporting our research activities in 2023. The objective of this foundation is the development of French scientific knowledge in the field of renewable energies and in particular new generation batteries.

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The Dynamic Nuclear Polarization technique allow to overcome the low sensitivity of the NMR technique thanks to the principle of the transfer of spin polarization from electrons to nuclei.

Find this new equipment at the Spectropole of the Federation Sciences Chimiques Marseille

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Balaraman Kalyanaraman, PhD, the Harry R. and Angeline E. Quadracci Professor in Parkinson’s Research Endowment and professor of biophysics, received the Aix-Marseille University (AMU) Doctor Honoris Causa title on April 9, 2024, in Marseille, France. The researchers who introduced Dr. B.Kalyanaraman were Didier Gigmes, directeur au CNRS, Olivier Ouari, professeur des universités, Hakim Karoui, maître de conférence et Micael Hardy, maître de conférence.

The mechanism of photolysis of carbon monoxide from myoglobin, predicted by Miquel Huix-Rotllant (CT, ICR), has been confirmed experimentally by time-resolved serial femtosecond crystallography (TR-SFX). This study has been published in Nature.

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Congratulations to Inès Jacquet from the PCR team who won the prize for best oral communication at the 31st Young Research Fellows Meeting of the SCT for her work on the modulation of position 2 of 3-nitroimidazo[1,2-a]pyridine using TDAE strategy: Exploration of antileishmanial structure-activity relationships!

Congratulations to Dr Marie Juramy, who received the 2022 AMU thesis prize for her work on the study of crystallization by solid-state Nuclear Magnetic Resonance (NMR) and Dynamic Nuclear Polarization (DNP). This thesis was supervised by Dr. Pierre Thureau and Prof. Stéphane Viel from the SACS team.

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American and SREP’s team researchers developed mitochondria-targeted atovaquone (Mito-ATO) capable of targeting cancer cells and having in vivo antitumor activity. They also found that Mito-ATO promotes anti-lung cancer immunity by reshaping the tumor microenvironment (TIME) and enhancing energy metabolism of anti-tumor immune cells.

Congratulations to Nina Girard-Perier who received the AMU 2021 thesis prize for her work on the impact of ionizing radiation (gamma, electron beam and X-rays) on plastic bags used for biopharmaceutical and biotechnological applications. Thesis funded by Sartorius (director: Dr Samuel Dorey) and supervised by Prof. Nathalie Dupuy from IMBE and Sylvain Marque from ICR.

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